Journal of Occupational Health and Epidemiology

en Spirometry-Based Airflow Obstruction and Pulmonary Function in Type 2 Diabetes: A Cross-Sectional Study Epidemiology Original Article <div style="text-align: justify;">Background: Systemic inflammation, oxidative stress, and microvascular dysfunction may predispose individuals with diabetes to impaired lung function. This cross-sectional study aimed to ascertain pulmonary function, the prevalence of spirometric airflow obstruction consistent with COPD, as well as associated factors among adults with type 2 diabetes in Southwest Iran. Materials & Methods: This cross-sectional study included 732 adults with type 2 diabetes, aged 35–70 years, enrolled in the Shahrekord PERSIAN Cohort Study. Demographic, comorbidities, anthropometric measurements, and spirometry findings were collected according to the standardized cohort protocol. Chi-square test, Fisher's exact test, and multivariable logistic regression analyses were undertaken to identify factors related to spirometric airflow obstruction. Spirometric patterns were classified as obstructive, restrictive, mixed, and normal based on standard criteria. Results: The prevalence of spirometric airflow obstruction was 8.5% (62/732). The most common pattern was restrictive (467, 63.8%), followed by mixed (47, 6.4%) and obstructive (15, 2.0%). In the multivariable logistic regression model, alcohol use (OR = 2.23; 95% CI: 1.09, 4.56), marital status (OR = 2.62; 95% CI: 1.14, 6.00), and chronic pulmonary disease (OR = 2.59; 95% CI: 1.21, 5.53) were independently linked to airflow obstruction. Conclusions: This study indicated a notable prevalence of spirometric airflow obstruction among adults with type 2 diabetes, with restrictive abnormalities being the predominant pattern. These findings offer preliminary epidemiological evidence for respiratory impairment in this population and establish a baseline for future longitudinal as well as interventional studies.</div> Chronic Obstructive Pulmonary Disease,Type 2 Diabetes Mellitus,Pulmonary Function,Spirometry,Respiratory Function Test, 93 101 http://johe.rums.ac.ir/browse.php?a_code=A-10-1068-1&slc_lang=en&sid=1 Samaneh Torkian torkiansamane72@gmail.com 22400319475328460014111 22400319475328460014111 No Assistant Prof., Dept. of Epidemiology and Biostatistics, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran. Ali Ahmadi aliahmadi2007@gmail.com 22400319475328460014112 22400319475328460014112 Yes Professor, Dept. of Epidemiology and Biostatistics, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran. Fatemeh Zeynab Kiani fatemezeynabkiani@gmail.com 22400319475328460014113 22400319475328460014113 No Ph.D Student in Epidemiology, Dept. of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Ph.D Student in Epidemiology, Dept. of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Hamid Rouhi hammfer@yahoo.com 22400319475328460014114 22400319475328460014114 No Retired Associate Prof., Dept.of pulmonary, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran. Akbar Soleymani Babadi dr.akbarsoleymani@yahoo.com 22400319475328460014115 22400319475328460014115 No Associate Prof., Dept. of Internal Medicine, School of Medicine, Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, Iran.