en Occupational Health Original Article <p style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Arial;"><a name="OLE_LINK26"></a><a name="OLE_LINK25"><strong>Background:</strong></a> Some factors, such as burnout and job satisfaction, may affect patient safety culture. This study aimed to examine the association between burnout, job satisfaction and patient safety culture among medical staff of the Qom University of Medical Sciences in 2020.<br> <strong>Materials and Methods:</strong> This descriptive-correlative study was conducted on 248 medical staff members of the Qom University of Medical Sciences in 2020. The demographic checklist, the standard hospital survey on patient safety culture (HSOPSO), the Maslach burnout inventory, and the job satisfaction questionnaire were used for data collection. Content validity of the questionnaires was evaluated based on expert judgments. The Cronbach&#39;s alpha coefficient was 78 and 41% for the Maslach burnout questionnaire and the JDI questionnaire, respectively. Besides, the Pearson&#39;s correlation coefficient, the independent t-test, and the analysis of variance were used to analyze the data via SPSS software<span dir="RTL">.</span><br> <strong>Results: </strong>This study included 40 (16.1%) males and 208 (83.9%) females with the mean age of 32.04 &plusmn; 7.9 years. The mean and SD of the HSOPSO, JID, and frequency of burnout scores were 135.4 &plusmn; 10.1, 68.07 &plusmn; 13.2, and 53.8 &plusmn; 4.5, respectively. This study showed that job burnout has a significantly negative association with patient safety culture (r= -0.53, P < 0.000). In contrast, there was a statistically significant positive association between job satisfaction and patient safety culture (r= 0.643, P < 0.000).<br> <strong>Conclusion:</strong> The findings of this study indicated that both factors of job satisfaction and burnout might play a significant role in patient safety. Thus, top medical managers must provide appropriate conditions for employees to improve patient safety.<span dir="RTL"></span></span></span></p> Burnout,Job Satisfaction,Patient Safety,Medical Staff, 127 133 http://johe.rums.ac.ir/browse.php?a_code=A-10-134-4&slc_lang=en&sid=1 Azadeh Asgarian azadeh.asgarian@yahoo.com 22400319475328460011893 22400319475328460011893 No MSc of Healthcare Services Management, Izadi Hospital, Qom University of Medical Sciences, Qom, Iran. Qom University of Medical Sciences Roghayeh Sadeghi r.sadeghi@gmail.com 22400319475328460011894 22400319475328460011894 No BSc of Nursing, Izadi Hospital, Qom University of Medical Sciences, Qom, Iran. Qom University of Medical Sciences Fatemeh Abolhasani fatemeh1979a@yahoo.com 22400319475328460011895 22400319475328460011895 No BSc of Nursing, Izadi Hospital, Qom University of Medical Sciences, Qom, Iran. Qom University of Medical Sciences Abolfazl Mohammadbeigi beigi60@gmail.com 22400319475328460011896 22400319475328460011896 No Professor, Dept. of Epidemiology and Biostatistics, Faculty of Health, Qom University of Medical Sciences, Qom, Iran. Qom University of Medical Sciences Alireza Omidi Oskouei 22400319475328460011897 22400319475328460011897 No Assistant Prof., Dept. of Public Health, Faculty of Health, Qom University of Medical Sciences, Qom, Iran. Qom University of Medical Sciences Ahmad Soltanzadeh soltanzadeh.ahmad@gmail.com 22400319475328460011898 22400319475328460011898 Yes Assistant Prof., Dept. of Occupational Safety & Health Engineering, Faculty of Health, Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran Qom University of Medical Sciences