Journal of Occupational Health and Epidemiology
J Occup Health Epidemiol
Medical Sciences
http://johe.rums.ac.ir
224
admin
2251-8096
2252-0902
10.61186/johe
0
en
jalali
1400
10
1
gregorian
2022
1
1
11
1
online
1
fulltext
en
The Survival Rate of Patients with Colorectal Cancer in Kerman Province of Iran from 2007 to 2016
Epidemiology
Original Article
<span style="font-size:12px;"><span style="font-family:Arial;"><span style="line-height:200%"><b><span style="line-height:200%"><span style="color:black">Background:</span></span></b><span style="line-height:200%"><span style="color:black"> This paper presents the conditional relative survival rates of colorectal cancer (CRC) and associated prognostic factors in the Kerman province, the largest province in the south of Iran. Scince CRC is the fifth common cancer in this province, this study aimed to provide more detailed statistics on the survival rate of CRC patients.</span></span><br>
<span style="line-height:200%"><b><span style="color:black">Materials and Methods:</span></b><span style="color:black"> This survival analysis study used the national population-based cancer registry data to estimate the survival rate in 1705 patients with CRC from 2007 to 2016. The Kaplan–Meier estimator and Log-rank test were used to plot survival curves and assess differences in survival rates. Univariate analysis and Cox proportional-hazards model were also used to determine association between CRC-related factors and patient survival. </span><br>
<b><span style="color:black">Results:</span></b><span style="color:black"> The 5-year survival rate for patients with CRC was 51.9%. This rate was significantly higher in the stage with localized lesions compared with those of regional and distant (p<0.001). <a name="_Hlk52200403">The survival rate in patients undergoing surgical treatment was higher than that of patients receiving chemotherapy </a>(p<0.001). Increased age, low tumor differentiation, the stage with distant tumors, and right-sided colon cancer (RCC) were associated with lower survival (p<0.001).</span><br>
<b><span style="color:black">Conclusions:</span></b><span style="color:black"> The tumor stage was significantly correlated with the survival rate of patients. Despite advances in the diagnosis and treatment of CRC in Iran and worldwide, the survival rate of patients in this study was low. Since many factors affect this rate, further studies are needed to identify its prognostic factors in Kerman</span></span><span style="line-height:200%"><span style="font-family:"Times New Roman","serif""></span></span></span>.</span></span>
Colorectal Neoplasms,Survival Rate,Kaplan–Meier Estimate,Proportional Hazards Models,Confidence Interval (CI),
1
9
http://johe.rums.ac.ir/browse.php?a_code=A-10-426-1&slc_lang=en&sid=1
Elham
Hashemipour
elham_hashemipour@yahoo.com
2240031947532846007675
2240031947532846007675
No
MSc in Epidemiology, Dept. of Epidemiology and Biostatistics, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Rafsanjan University of Medical Sciences
Reza
Vazirinejad
rvazirinejad@yahoo.co.uk
2240031947532846007676
2240031947532846007676
No
Professor, Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Rafsanjan University of Medical Sciences
Mahmoud
Sheikh Fatholahi
mamoosh502002@yahoo.com
2240031947532846007677
2240031947532846007677
No
Assistant Prof., of Biostatistics, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Iran University of Medical Sciences
Mohsen
Rezaian
moeygmr2@yahoo.co.uk
2240031947532846007678
2240031947532846007678
Yes
Professor, Head of Dept. of Epidemiology and Biostatistics, Occupational Environmental Research Center, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Rafsanjan University of Medical Sciences