en Occupational Health Review Article <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Arial;"><span style="line-height:250%"><b><span style="color:black">Background:</span></b><span style="color:black"> Covid-19 disease has posed a serious challenge to countries&#39; healthcare systems at the present outbreak. Meanwhile, the healthcare providers&#39; mental health has been affected. This systematic review and meta-analysis aimed to investigate the pooled prevalence of depression, anxiety, and insomnia among healthcare workers in a short period during the COVID-19 pandemic.</span></span><br> <span style="line-height:250%"><b><span style="color:black">Materials and Methods:</span></b><span style="color:black"> A systematic search was conducted through Web of Science, Scopus, Medline, and Embase databases, as well as preprint servers of medRxiv and SSRN, up to August 24, 2020. </span></span><br> <span style="line-height:250%"><b><span style="color:black">Results:</span></b><span style="color:black"> This review comprised 69 articles with a total sample size of 108,931 individuals selected from medical staff. The pooled prevalence of anxiety, depression, and insomnia were 37% (95% CI: 31 to 43%), 34% (95% CI: 29 to 38%), and 39% (95% CI: 25 to 53%), respectively. A subgroup analysis showed that the prevalence of anxiety, depression, and insomnia was higher in females and nurses than in others.</span></span><br> <span style="line-height:250%"><b><span style="color:black">Conclusions:</span></b><span style="color:black"> Findings indicated a high impact of the COVID-19 pandemic on the prevalence of anxiety, depression, and insomnia among medical professionals involved in the crisis with a variety of territories and occupations of both genders.</span><span style="line-height:250%"></span></span></span></span><br> &nbsp;</div> COVID-19,Anxiety,Depression,Insomnia,Health Personnel, 48 66 http://johe.rums.ac.ir/browse.php?a_code=A-10-446-1&slc_lang=en&sid=1 Vida Rezaei-Hachesu rezaeividaoh@gmail.com 22400319475328460011268 22400319475328460011268 No PhD Candidate in Occupational Health Engineering, Dept, of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Tehran University of Medical Sciences Shadi Naderyan Fe’li naderyan67@gmail.com 22400319475328460011269 22400319475328460011269 No PhD Candidate in Epidemiology, Dept. of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Tehran University of Medical Sciences Khadije Maajani khadije.maajaani@gmail.com 22400319475328460011270 22400319475328460011270 No Instructor of Occupational Health Engineering, Dept. of Occupational Health Engineering, School of Public Health, North Khorasan University of Medical Sciences, Bojnurd, Iran. North Khorasan University of Medical Sciences Farideh Golbabaei fgolbabaei@tums.ac.ir 22400319475328460011271 22400319475328460011271 Yes Professor of Occupational Health Engineering, Dept, of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Tehran University of Medical Sciences