en Epidemiology Original Article <div style="text-align: justify;"><span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Background: </span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">The outbreak of the Covid-19 has been a serious threat to the health and lives of many people. This study aimed to determine the survival rate and its contributing factors in Covid-19 patients who were hospitalized in hospitals in Fars province.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Materials and Methods:</span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> This study is a hospital-based carried out on 119429 of Covid-19 hospitalized patients in the south of Iran within 2019 &ndash; 2022. Information of demographics and clinical characteristics, symptoms, and comorbidity of patients were extracted from medical records. The Kaplan&ndash;Meier curve and the Log rank test were used to compare survival rate in different groups. Cox regression was employed to determine the factors that affect survival.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Results:</span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> The mean age of the participants was 51.5 year. The density incidence of death was estimated to be 16.8, 4.6, and 43.9 per 1000 person-days for all of patient, intensive care unit patients, and intubated patients, respectively. The Multiple Cox Regression results suggested that risk of mortality is 5.61 times higher in patients over 75 years, 3 times higher in patients admitted to the intensive care unit, and 3.4 times higher in intubated patients. Also, the risk of mortality was higher in men and those with underlying disease.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> We found out that being elder, being a male, hospitalization in the intensive care unit, and being intubated would increase the risk of mortality. Thus, it is treatment management of hospitalized patients is necessary, especially elderly patients and those with underlying diseases.</span></span></span></span></span></span></span></div> Survival,Covid-19,Mortality,Risk Factors,Iran, 1 9 http://johe.rums.ac.ir/browse.php?a_code=A-10-640-1&slc_lang=en&sid=1 Alireza Mirahmadizadeh mirahmadia@sums.ac.ir 22400319475328460010473 22400319475328460010473 No Associate Prof., Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Shiraz University of Medical Sciences Seyed Sina Dehghani Dehghani.sina77@gmail.com 22400319475328460010474 22400319475328460010474 No Medical Doctor, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Shiraz University of Medical Sciences Mohammad Reza Karimi Karimi.mrk@gmail.com 22400319475328460010475 22400319475328460010475 No Medical Doctor, Technical Assistant of Health Vice Chancellor, Shiraz University of Medical Sciences, Shiraz, Iran. Shiraz University of Medical Sciences Leila Moftakhar moftakhar_p@yahoo.com 22400319475328460010476 22400319475328460010476 Yes Ph.D. in Epidemiology, Abadan University of Medical Sciences, Abadan, Iran Abadan University of Medical Sciences