Journal of Occupational Health and Epidemiology

en Comparing Hematological Indices of People with Iron Deficiency Anemia, Thalassemia Minor and Major, and Healthy People Epidemiology Original Article <div style="text-align: justify;">Background: This study aimed to evaluate three hematological indices in children and adolescents with iron deficiency anemia, thalassemia minor and major and healthy people. Materials and Methods: In this descriptive cross-sectional study, 164 patients were selected based on the inclusion and exclusion criteria, and divided into four groups (n=41): iron deficiency anemia, thalassemia minor, thalassemia major, and healthy people. The results obtained from the tests were recorded in the patients' checklist. Mann-Whitney test, Wilcoxon test, ROC curve and area under the curve were adopted for data analysis using SPSS Statistics V21.0. Results: The mean age of patients was 13.07±3.82 years, of which 100 (62.5%) were men. There is a significant difference due to the hemoglobin concentration (Hb) index in two-by-two comparison of the groups (P<0.001), but this difference was not seen between iron deficiency and thalassemia minor groups (P=0.159). This difference was substantial (P<0.001) in terms of mean corpuscular volume (MCV) index, although it was only seen between the iron deficiency and thalassemia major groups (P=0.225). Finally, this mean difference was reported in Serum ferritin index (P<0.001), but no difference was observed between healthy group and thalassemia minor group (P=0.802). Conclusion: The results showed that there is a difference in meanHb, MCV, and Ferritin levels between the studied groups, and the Hb and Ferritin indices are favorable for iron deficiency anemia, and the Hb and MCV indices are favorable to distinguish the thalassemia minor and major from healthy people.</div> Ferritin,Thalassemia Minor,Beta-Thalassemia,Iron Deficiency,Hemoglobin Concentration,Mean Corpuscular Volume, 62 69 http://johe.rums.ac.ir/browse.php?a_code=A-10-735-1&slc_lang=en&sid=1 Akram Hemmatipour hematipour.a64@gmail.com 22400319475328460010914 22400319475328460010914 No M.Sc. in Nursing, Dept. of Nursing, Abadan University of Medical Sciences, Abadan, Iran. Abadan University of Medical Sciences Razieh Jalakani jalakani.r@gmail.com 22400319475328460010915 22400319475328460010915 No M.Sc. in Hematology, Dept. of Hematology and Blood Banking, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Shoushtar Faculty of Medical Sciences Azam Jahangirimehr jahangirimehr.a@gmail.com 22400319475328460010916 22400319475328460010916 No M.Sc. in Biostatistics, Dept. of Public Health, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Shoushtar Faculty of Medical Sciences Bijan Keikhaei kechaii@gmail.com 22400319475328460010917 22400319475328460010917 No Associate Prof., Thalassemia & Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Ahvaz Jundishapour University of Medical Sciences Darush Rokhafrooz ricohafraz@gmail.com 22400319475328460010918 22400319475328460010918 No Associate Prof., Nursing Care Research Center in Chronic Diseases, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Ahvaz Jundishapour University of Medical Sciences Seyedeh Moloud Rasouli Ghahfarokhi 22400319475328460010919 22400319475328460010919 Yes M.Sc. in Nursing, Nursing Care Research Center in Chronic Diseases, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.