en Epidemiology Original Article <div style="text-align: justify;"><span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Background:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Industrial workers are vulnerable to the development of kidney disease owing to the associated risk factors and work-related fatigue. It is essential to compare the prevalence of CKDu among workers using different (eGFR) equations. This study aims to evaluate prevalence of CKDu among industrial workers and compare using different eGFR equations.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Materials and Methods:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> A cross-sectional study was conducted on 132 industrial workers (91 men and 41 women). Serum creatinine was analysed and eGFR values were calculated based on the modification of diet in renal disease-175 (MDRD-175), MDRD-186, Cockcroft Gault (CG), and chronic kidney disease-epidemiology collaboration (CKD-EPI) equations. CKDu stages were ascertained using KDIGO guidelines.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Results:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Average age and BMI of the workers were 33.5 years and 24 kg/m2, respectively. Mean serum creatinine level was 1.0 (0.3&ndash;1.8) mg/dL. The CKD-EPI equation revealed highest mean eGFR value followed by CG, MDRD-186, and MDRD-175. CKDu prevalence among workers was 9.1% with MDRD-175, 4.6% as per MDRD-186, 9.9% in CG, and 3.1% as per CKD-EPI equations. Notably, the mean creatinine and eGFR values were lower in female workers when compared to males. Further, the prevalence of CKDu stage 2 was higher in females, while stage 3 (eGFR < 60 mL/min/m&sup2;) was significantly more prevalent among males than females.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> The prevalence of CKDu was found to be significantly higher among male than female workers. The rates of CKDu determined using MDRD-186 and CKD-EPI equations were comparable and can be used to predict the CKDu prevalence among industrial workers from different occupational settings.</span></span></span></span></span></span></span></div> Chronic Kidney Disease of Unknown Etiology,Workers,Glomerular Filtration Rate, 108 116 http://johe.rums.ac.ir/browse.php?a_code=A-10-51-3&slc_lang=en&sid=1 Raju Nagaraju raju86mys@yahoo.com 22400319475328460013191 22400319475328460013191 No Ph.D. in Biochemistry, Dept. of Biochemistry, Regional Occupational Health Centre Southern, Kannamangala Post Poojanahalli, Devanahalli, Bengaluru, India. Kannamangala Post Poojanahalli, Kalahasthi Ravi Babu kalahasthi20012002@yahoo.co.in 22400319475328460013192 22400319475328460013192 Yes Ph.D. in Biochemistry, Dept. of Biochemistry, Regional Occupational Health Centre Southern, Kannamangala Post Poojanahalli, Devanahalli, Bengaluru, India. Kannamangala Post Poojanahalli Surendar Jakkam surenderjakkam@gmail.com 22400319475328460013193 22400319475328460013193 No M.D. in Occupational Medicine, Dept. of Occupational Medicine, Regional Occupational Health Centre (Southern), Poojanahalli, Bengaluru, India. Regional Occupational Health Centre (Southern) Ravi Prakash Jamalpur j.raviprakash24@gmail.com 22400319475328460013194 22400319475328460013194 No M.Sc. in Biochemistry, Dept. of Biochemistry, Regional Occupational Health Centre Southern, Kannamangala Post Poojanahalli, Devanahalli, Bengaluru, India. Regional Occupational Health Centre Southern, Kannamangala Post Poojanahalli, Vinay Kumar Adepu vinu0586@gmail.com 22400319475328460013195 22400319475328460013195 No Ph.D. in Biochemistry, Dept. of Biochemistry, Regional Occupational Health Centre Southern, Kannamangala Post Poojanahalli, Devanahalli, Bengaluru, India. Regional Occupational Health Centre Southern, Kannamangala Post Poojanahalli,