en Occupational Health Case Study <div style="text-align: justify;"><span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Background: </span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Printing industry workers face hazards from noise and lead exposure. This study investigates the combined effects of lead and noise on malondialdehyde (MDA) levels in these workers, as previous research has focused on isolated effects. This study aimed at assessing the impact of simultaneous lead and noise exposure on the health of people working in the printing industry.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Materials and Methods:</span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:"> Using TENMARS ELECTRONICS sound-meter following ISO9612:2009, malondialdehyde (MDA) levels were measured using Buege and Aust spectrophotometer Model CE1010 CECIL series 1000. Blood lead analysis followed NIOSH8003 method. Data were statistically analyzed using SPSS 20.0 with Pearson and ANOVA tests. The Kolmogorov-Smirnov test was employed to check the normality of the data.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Results:</span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:"> The study found that the die-cut unit had significantly higher daily noise exposure (mean &plusmn; standard deviation = 87.71 &plusmn; 1.469 dB) compared to other units. Additionally, the printing unit had significantly higher lead concentration (mean &plusmn; standard deviation = 0.1431 &plusmn; 0.02 ppb) and malondialdehyde (MDA) concentration (mean &plusmn; standard deviation = 0.9963 &plusmn; 0.238 mmol/lit) compared to other units.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:150%"><span courier="" new="" style="font-family:"><span style="color:black"><b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Conclusion:</span></span></span></b><span style="font-size:11.0pt"><span style="line-height:150%"><span arial="" style="font-family:"> The study found a strong link between blood lead levels and malondialdehyde (MDA) concentration in printing industry workers. However, no significant correlation was found between MDA levels and noise exposure or the combined exposure to noise and lead. These findings emphasize the need to address lead exposure in the printing industry to protect workers&#39; health and prevent elevated MDA levels.</span></span></span></span></span></span></span></div> Lead,Noise,Malondialdehyde,Printing, 194 200 http://johe.rums.ac.ir/browse.php?a_code=A-10-566-1&slc_lang=en&sid=1 Zhaleh Sedghi Noushabadi zhaleh.sedghy@gmail.com 22400319475328460010728 22400319475328460010728 No M.Sc. in Occupational Health, Research Committee, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. Iran University of Medical Sciences Soqrat Omari Shekaftik soqratamary@gmail.com 22400319475328460010729 22400319475328460010729 No Ph.D. Student in Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Tehran University of Medical Sciences Narges Moghadasi n.moghadasi.work@gmail.com 22400319475328460010730 22400319475328460010730 No M.Sc. Student in Occupational Health, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. Iran University of Medical Sciences Anahita Montazeri anna.montazeri@gmail.com 22400319475328460010731 22400319475328460010731 No B.Sc. in Occupational Health, School of Health, Safety and Environment, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Shahid Beheshti University of Medical Sciences Azadeh Ashtarinezhad ashtarinezhad.a@iums.ac.ir 22400319475328460010732 22400319475328460010732 Yes Assistant Prof., Dept. of Occupational Health, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. Iran University of Medical Sciences