Volume 5, Issue 1 (Winter 2016)                   JOHE 2016, 5(1): 53-62 | Back to browse issues page

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Nadri F, Khavanin A, Mazaheri Z, Soleimanian A. Effect of noise pollution on male fertility (Review). JOHE. 2016; 5 (1) :53-62
URL: http://johe.rums.ac.ir/article-1-213-en.html
1- Dept. of Occupational Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
2- Dept. of Occupational Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. , khavanin@Modares.ac.ir
3- Dept. of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Abstract:   (6208 Views)

Background: Noise as a most common harmful physical agent in workplaces has some effects on the exposed persons such as hearing threshold reduction, increasing blood pressure, and interference with the speech. The adverse side-effect of noise is one of the scientific areas that have seldom been considered by researchers. The aim of this study was to investigate the effects of occupational noise on the male fertility (human and experimental animals) to be finally able to provide solutions for the future orientation of research studies, and on the other hand, to increase awareness in industrial divisions about effects of noise stress on workers fertility.

Materials and Methods: In this study, we conducted the bibliographic search in PubMed and Google Scholar databases and studies about effects of workplaces noise on the male fertility with keywords such as fertility, noise, and testicular damage were selected.

Results: Male infertility is a major health problem in the world. According to different study, Noise can impact on testis weight, sperm parameters (count, viability, motility and morphology), sexual hormones, testicular tissue, oxidative stress and finally infertility.

Conclusions: The results of this study shows that noise exposure plays an important role as an environmental risk factor for male fertility; therefore, it is necessary to formulate guidelines for occupational exposure limits of noise effects, exposure time, use or not usage of supplemental antioxidants and to consider fertility and not be confined merely to the effects of noise on hearing system.

Keywords: Noise [MeSH], Fertility [MeSH], Workplace [MeSH]
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Short Report: Original Article | Subject: Occupational Health
Received: 2016/12/12 | Accepted: 2016/12/25 | ePublished: 2017/02/25

1. World Health Organization. Burden of disease from environmental noise: Burden of disease from environmental noise: Quantification of healthy life years lost in Europe. Copenhagen, Denmark: World Health Organization Regional Office for Europe; 2011. Available from:
2. Passchier-Vermeer W, Passchier WF. Noise exposure and public health. Environ Health Perspect 2000; 108(Suppl 1):123-31.
3. Swami CG, Ramanathan J, Jeganath CCh. Noise exposure effect on testicular histology, morphology and on male steroidogenic hormone. Malays J Med Sci 2007; 14(2):28-35.
4. Armario A, Castellanos JM. Effect of noise stress on testosterone secretion in mice. IRCS Medical Science-Biochemistry 1984; 12(3):208-10.
5. Xue L, Zhang D; Xiaokaiti·Yibulayin, Wang T, Shou X. Effects of high frequency noise on female rat's multi-organ histology. Noise Health 2014; 16(71):213-7.
6. Chamkori A, Shariati M, Moshtaghi D, Farzadinia P. Effect of noise stress on the hormonal and semen analysis parameters in industrial worker of Bushehr, Iran. Crescent Journal of Medical and Biological Sciences 2015; 3(2):45-50.
7. Tak S, Davis RR, Calvert GM. Exposure to hazardous workplace noise and use of hearing protection devices among US workers—NHANES, 1999-2004. Am J Ind Med 2009; 52(5):358-71.
8. Hammer MS, Swinburn TK, Neitzel RL. Environmental noise pollution in the United States: developing an effective public health response. Environ Health Perspect 2014; 122(2):115-9.
9. Ghotbi MR, Monazzam MR, Khanjani N, Nadri F, Bellah Fard SM. Driver exposure and environmental noise emission of Massey Ferguson 285 tractor during operations with different engine speeds and gears. Afr J Agric Res 2013; 8(8):652-9.
10. Monazzam M, Nadri F, Khanjani N, Ghotbi Ravandi MR, Nadri H, Barsam T, et al. Tractor drivers and bystanders noise exposure in different engine speeds and gears. Journal of Military Medicine 2012; 14(2):149-54.
11. Ghotbi Ravandi MR, Nadri F, Khanjani N, Ahmadian M. Occupational noise exposure among the workers of Kerman Cement Plant, 2009. Journal of Occupational Health and Epidemiology 2012; 1(1):17-23.
12. Jafari MJ, Karimi A, Haghshenas M. Extrapolation of experimental field study to a national occupational noise exposure standard. International Journal of Occupational Hygiene 2010; 2(2):63-8.
13. Lasheen SS, Refaat SH, EI-Nefiawy NE, Abd-Elgawad RM, Othman AI, Olama NKh. Developmental characteristics of rat testicular tissue and the impact of chronic noise stress exposure in the prenatal and postnatal periods. Anat Physiol 2015; doi:10.4172/2161-0940.S4-00.
14. Shaha Ch, Tripathi R, Mishra DP. Male germ cell apoptosis: regulation and biology. Philosophical Transactions of the Royal Society B: Biological Sciences 2010; 365(1546):1501-15.
15. Working PK. Male reproductive toxicology: comparison of the human to animal models. Envion Health Perspect 1988; 77(3):37-44.
16. Drake RL, Vogl W, Mitchell AWM. Gray's anatomy for students. London: Elsevier/Churchill Livingstone; 2005.
17. Jones R, Lopez K. Human reproductive biology. 4th ed. Cambridge, Massachusetts: Academic Press; 2014.
18. Hjollund NHI, Storgaard L, Ernst E, Bonde JP, Olsen J. The relation between daily activities and scrotal temperature. Reprod Toxicol 2002; 16(3):209-14.
19. Griffin JE, Ojeda SR. Textbook of endocrine physiology. 5th ed. Oxford, England: Oxford University Press; 2004.
20. Costabile R. Anatomy and physiology of the male reproductive system. 1st ed. Cambridge, England: Cambridge University Press; 2013. Chapter 1.
21. Dyer S, Chambers GM, de Mouzon J, Nygren KG, Zegers-Hochschild F, Mansour R, et al. International Committee for Monitoring Assisted Reproductive Technologies world report: Assisted Reproductive Technology 2008, 2009 and 2010. Hum Reprod 2016; 31(7):1588-609.
22. Yuce A, Turk G, Ceribasi S, Sonmez M, Ciftci M, Guvenc M. Effects of cinnamon (Cinnamomum zeylanicum) bark oil on testicular antioxidant values, apoptotic germ cell and sperm quality. Andrologia 2013; 45(4):248-55.
23. Vaziri MH, Sadighi Gilani MA, Kavousi A, Firoozeh M, Khani Jazani R, Taqi Dizaj AV, et al. The relationship between occupation and semen quality. Int J Ferti Steril 2011; 5(2):66-71.
24. Kamali M, Baghestani AR, Kashfi F, Kashani H, Tavajohi Sh, Amirchaghmaghi E. A survey on infertility in Royan Institute. Infertility 2007; 1(1):23-6.
25. Ghahramani F, Ghaem H. The effective factors on men infertility: a case-control study. Journal of Gorgan University of Medical Sciences 2005; 7(2):42-5.
26. Vahidi S, Ardalan A, Mohammad K. Prevalence of primary infertility in the Islamic Republic of Iran in 2004-2005. Asia Pac J Public Health 2009; 21(3):287-93.
27. Zegers-Hochschild F, Adamson GD, de Mouzon J, Ishihara O, Mansour R, Nygren K, et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril 2009; 92(5):1520-4.
28. Grzanna R, Lindmark L, Frondoza CG. Ginger-an herbal medicinal product with broad anti-inflammatory actions. J Med Food 2005; 8(2):125-32.
29. Guzick DS, Overstreet JW, Factor-Litvak P, Brazil CK, Nakajima ST, Coutifaris C, et al. Sperm morphology, motility, and concentration in fertile and infertile men. N Engl J Med 2001; 345(19):1388-93.
30. Carlsen E, Giwercman A, Keiding N, Skakkebæk NE. Evidence for decreasing quality of semen during past 50 years. BMJ 1992; 305(6854):609-13.
31. Brugh VM 3rd, Lipshultz LI. Male factor infertility: evaluation and management. Med Clin North Am 2004; 88(2):367-85.
32. Pierik FH, Van Ginneken AM, Dohle GR, Vreeburg JTM, Weber RFA. The advantages of standardized evaluation of male infertility. Int J Androl 2000; 23(6):340-6.
33. Nevin CA. Effects of lifestyle and environment on human sperm. [Thesis PhD]. Manchester, England: Manchester Metropolitan University; 2016.
34. Lue Y, Sinha Hikim AP, Wang Ch, Im M, Leung A, Swerdloff RS. Testicular heat exposure enhances the suppression of spermatogenesis by testosterone in rats: the “Two-Hit” approach to male contraceptive development. Endocrinology 2000; 141(4):1414-24.
35. Paranagama PA, Wimalasena S, Jayatilake GS, Jayawardena AL, Senanayake UM, Mubarak AM. A comparison of essential oil constituents of bark, leaf, root and fruit of cinnamon (Cinnamomum zeylanicum Blum) grown in Sri Lanka. J Natl Sci Found 2001; 29(3-4):147-53.
36. Diab AA, Hendawy A, Asala AK, Ibrahim SS, Hassan MA. Effect of noise stress on pituitary gonadal axis in albino rats. J Am Sci 2012; 8(11):198-202.
37. Jalali M, Saki Gh, Sarkaki AR, Karami K, Nasri S. Effect of noise stress on count, progressive and non-progressive sperm motility, body and genital organ weights of adult male rats. J Hum Reprod Sci 2012; 5(1):48-51.
38. Ruffoli R, Carpi A, Giambelluca MA, Grasso L, Scavuzzo MC, Giannessi FF. Diazepam administration prevents testosterone decrease and lipofuscin accumulation in testis of mouse exposed to chronic noise stress. Andrologia 2006; 38(5):159-65.
39. Ghanbari M, Mortazavi SB, Khavanin A, Khazaei M. Simultaneous effects of exposure to microwaves and noise on male rat'sperm parameters and total antioxidant capacity. Health Scope 2013; 1(4):179-85.
40. Vosoughi Sh, Khavanin A, Salehnia M, Asilian Mahabadi H, Soleimanian A. Effects of simultaneous exposure to formaldehyde vapor and noise on mouse testicular tissue and sperm parameters. Health Scope 2012; 1(3):110-7.
41. Saki G, Jasemi M, Sarkaki AR, Fathollahi A. Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress. Noise Health 2013; 15(64):194-8.
42. Abdollahi MB, Khavanin A, Vosoughi S, Amanpour S, Kaydani M, Noorloie S. The effects of noise exposure on sperm parameters (count, motility and viability) mice. Journal of Acoustical Engineering Society of Iran 2015; 3(1):66-72.
43. Fathollahi A, Jasemi M, Saki G. Effect of noise stress on male rat fertility, and the protective effect of vitamins C and E on its potential effect. Arab J Urol 2013; 11(1):101-5.
44. Kenani M, Rajabzadeh A, Saki Gh, Khodadadi A, Sarkaki Al, Jafai A, et al. A survey of the relationship between noised pollution, honey and vitamin E and plasma level of blood sexual hormones in noise-exposed rats. Jentashapir Journal of Health Research 2015; 6(1):e27331. doi: 10.5812/jjhr.27331
45. Mohamed AF, Hanafy SM, Mahmoud A. The possible protective effect of black seed (Nigella Sativa) oil on the testes of adult male albino rat exposed to noise. Journal of Histology & Histopathology 2015; 2(21). doi:http://dx.doi.org/10.7243/2055-091X-2-21
46. Farzadinia P, Bigdeli M, Akbarzadeh S, Mohammadi M, Daneshi A, Bargahi A. Effect of noise pollution on testicular tissue and hormonal assessment in rat. Andrologia 2016; 48(9):869-73.
47. Pramanik P, Biswas S. Traffic noise: a silent killer of male gamete of albino rats. Al Ameen Journal of Medical Sciences 2012; 5(1):82-9.
48. Ahmadi R, Gohari A, Hooshmand M. The effect of noise stress on serum levels of LH, FSH and testosterone in male rats. Feyz Journal of Kashan University of Medical Sciences 2015; 19(1):24-9.
49. South T. Managing noise and vibration at work: a practical guide to assessment, measurement and control. 1st ed. Oxford, United Kingdom: Elsevier Butterworth-Heinemann; 2004.
50. Kelly JB, Masterton B. Auditory sensitivity of the albino rat. J Comp Physiol Psychol 1977; 91(4):930-6.
51. Campo P, Pouyatos B, Lataye R, Morel G. Is the aged rat ear more susceptible to noise or styrene damage than the young ear? Noise Health 2003; 5(19):1-18.
52. Lataye R, Campo P, Loquet G. Combined effects of noise and styrene exposure on hearing function in the rat. Hear Res 2000; 139(1-2):86-96.
53. Heffner HE, Heffner RS. Hearing ranges of laboratory animals. J Am Assoc Lab Anim Sci 2007; 46(1):20-2.
54. Shayne CG. Animal models in toxicology. 2nd ed. Boca Raton, Florida, United States: CRC Press, Taylor & Francis Group; 2006.
55. Cobo P, Murillo-Cuesta S, Cediel R, Moreno A, Lorenzo-García P, Varela-Nieto I. Design of a reverberant chamber for noise exposure experiments with small animals. Appl Acoust 2009; 70(8):1034-40.
56. Alvarez JG, Storey BT. Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa. Mol Reprod Dev 1995; 42(3):334-46.
57. Sikka SC. Oxidative stress and role of antioxidants in normal and abnormal sperm function. Front Biosci 1996; 1:e78-86.
58. Saki G, Jalali MA, Sarkaki AR, Karami K, Ahangarpoor A. Effect of supplementation of zinc on fertilization capacity of male rats exposed to noise stress. International Journal of Pharmaceutical Research and Allied Sciences 2016; 5(2):67-74.
59. Asgari Jahromi M, Movahedin M, Amanloo M, Mowla SJ, Mazaheri Z. The effects of calligonum extract on sperm parameters and the rate of apoptosis in aged male mice testis issue. Modares Journal of Medical Sciences: Pathobiology 2013; 16(1):41-54.
60. Hafez DA. Effect of extracts of ginger goots and cinnamon bark on fertility of male diabetic rats. J Am Sci 2010; 6(10):940-7.
61. Joshi K, Awte Sh, Bhatnagar P, Walunj S, Gupta R, Joshi SP, et al. Cinnamomum zeylanicum extract inhibits proinflammatory cytokine TNF: in vitro and in vivo studies. Research In Pharmaceutical Biotechnology 2010; 2(2):14-21.
62. Khaki A. Effect of Cinnamomum zeylanicumon on Spermatogenesis. Iran Red Crescent Med J 2015; 17(2):e18668.
63. Khaki A, Khaki AA, Hajhosseini L, Sadeghpour Golzar F, Ainehchi N. The anti-oxidant effects of ginger and cinnamon on spermatogenesis dys-function of diabetes rats. Afr J Tradit Complement Altern Med 2014; 11(4):1-8.
64. Mahmoudi MN, Hejazi S, Afshari F. The effect of hydroalcoholic extract of cinnamon on mice testis tissue. Biol Forum 2015; 7(1):1461-8.

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