Journal of Occupational
Health and Epidemiology
Rafsanjan university Of medical sciences
Volume 13, Issue 4 (Autumn 2024)
J Occup Health Epidemiol 2024, 13(4): 247-251 |
Back to browse issues page
Ethics code: IR.RUMS. REC.1398.195
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Vatankhah H, Ahmadinia H, Asadikaram M, Rezaei B, Rezaeian M, Jamali Z. The prevalence of Congenital Hypothyroidism in Rafsanjan in Southeast Iran During 2017-2019. J Occup Health Epidemiol 2024; 13 (4) :247-251
URL: http://johe.rums.ac.ir/article-1-774-en.html
URL: http://johe.rums.ac.ir/article-1-774-en.html
Related article in
Google Scholar
Google Scholar
Similar articles
Hajar Vatankhah1 
, Hassan Ahmadinia2 , Mina Asadikaram3 , Batool Rezaei4 , Mohsen Rezaeian5 , Zahra Jamali *6
, Hassan Ahmadinia2 , Mina Asadikaram3 , Batool Rezaei4 , Mohsen Rezaeian5 , Zahra Jamali *6
1- Assistant Prof, Clinical Research Development Unit (CRDU), Niknafs Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran & Assistant Prof, Dept. of Obstetrics and Gynecology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
2- Assistant Prof, Dept. of Epidemiology and Biostatistics, Occupational Environmental Research Center, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
3- Doctor of Medicine, Clinical Research Development Unit (CRDU), Ali-IbnAbi-Talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
4- B.Sc. in Midwifery, Health System Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
5- Prof, Dept. of Epidemiology and Biostatistics, Occupational Environmental Research Center, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
6- Assistant Prof, Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. ,Zahrajamali2959@gmail.com
2- Assistant Prof, Dept. of Epidemiology and Biostatistics, Occupational Environmental Research Center, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
3- Doctor of Medicine, Clinical Research Development Unit (CRDU), Ali-IbnAbi-Talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
4- B.Sc. in Midwifery, Health System Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
5- Prof, Dept. of Epidemiology and Biostatistics, Occupational Environmental Research Center, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
6- Assistant Prof, Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. ,
Article history
Received: 2024/02/18
Accepted: 2024/07/8
ePublished: 2025/03/12
Accepted: 2024/07/8
ePublished: 2025/03/12
Subject:
Epidemiology
Abstract: (337 Views)
Background: Congenital hypothyroidism (CH) is one of the most common endocrine diseases in newborns. Epidemiologic studies are very important to carry out more preventive assessments. This study evaluated the prevalence of CH in Rafsanjan in southeast Iran during 2017-2019.
Materials and Methods: In this descriptive study, we used the data collected from the CH screening of newborns in Rafsanjan, Kerman Province, Iran. The study population was 18832 newborns who had undergone a CH screening program according to the standard CH screening protocol in a public health center from March 2017 to March 2019. Diagnosed CH cases were compared with healthy newborns using chi-square.
Results: Overall, among this population, 94 cases were diagnosed with CH during the years 2017 to 2019. The prevalence of CH in Rafsanjan city was 4.99 per 1000 live births during 3 years. The frequency of thyroid dysfunction in the mother and birth weight under 2500 were higher among the CH group than the non-CH group (P < 0.001).
Conclusions: The study findings showed that the frequency of thyroid dysfunction in the mother and birth weight under 2500 were higher among the CH group than the non-CH group. Further studies with individual data and longitudinal are suggested to be more confident about the causality of the association.
Materials and Methods: In this descriptive study, we used the data collected from the CH screening of newborns in Rafsanjan, Kerman Province, Iran. The study population was 18832 newborns who had undergone a CH screening program according to the standard CH screening protocol in a public health center from March 2017 to March 2019. Diagnosed CH cases were compared with healthy newborns using chi-square.
Results: Overall, among this population, 94 cases were diagnosed with CH during the years 2017 to 2019. The prevalence of CH in Rafsanjan city was 4.99 per 1000 live births during 3 years. The frequency of thyroid dysfunction in the mother and birth weight under 2500 were higher among the CH group than the non-CH group (P < 0.001).
Conclusions: The study findings showed that the frequency of thyroid dysfunction in the mother and birth weight under 2500 were higher among the CH group than the non-CH group. Further studies with individual data and longitudinal are suggested to be more confident about the causality of the association.
Keywords: Congenital Hypothyroidism [MeSH], Prevalence [MeSH], Neonatal Screening [MeSH], Iran [MeSH]
References
1. Zhou J, Luo J, Lin J, Zeng Y, Qiu X, Zhu W, et al. Perinatal risk factors for congenital hypothyroidism: A retrospective cohort study performed at a tertiary hospital in China. Medicine (Baltimore). 2020;99(26):e20838. [DOI] [PMID] [PMCID]
2. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM. Williams Textbook of Endocrinology. 13th ed. Amsterdam, Netherlands: Elsevier; 2015. Chapter 3, Thyroid.
3. Larsen PR, Zavacki AM. The role of the iodothyronine deiodinases in the physiology and pathophysiology of thyroid hormone action. Eur Thyroid J. 2012;1(4):232-42. [DOI] [PMID] [PMCID]
4. Saunders M, Gorelick MH, Kliegman RM, Stanton BF, Geme JS, Schor NF, et al. Nelson textbook of pediatrics. Philadelphia, Pennsylvania, United States: Saunders Elsevier; 2011.
5. Barnes ND. Screening for congenital hypothyroidism: the first decade. Arch Dis Child. 1985;60(6):587-92. [DOI] [PMID] [PMCID]
6. Azizi F, Oladi B, Nafar Abadi MT, Haji Pour R. Screening for detection of congenital hypothyroidism in tehran: effect of iodine deficiency on transient elevation of TSH in children. Res Med. 1994;18(1):34-8. [Article]
7. Karamizadeh Z, Saneifard H, Amirhakimi G, Karamifar H, Alavi M. Evaluation of congenital hypothyroidism in Fars province, Iran. Iran J Pediatr. 2012;22(1):107-12. [PMID] [PMCID]
8. Baridkazemi S, Bahrami HR, Eftekhari Gol R, Mosa Farkhani E, Hoseini SJ. Investigation of the risk factors for congenital hypothyroidism in Iran: A population-based case-control study. J Pediatr Perspect. 2019;7(2):8951-8. [DOI]
9. Hashemipour M, Samei P, Kelishadi R, Hovsepian S, Hani Tabaei Zavareh N. A systematic review on the risk factors of congenital hypothyroidism. J Pediatr Rev. 2019;7(4):199-210. [DOI]
10. Mohammadi E, Baneshi MR, Nakhaee N. The Incidence of Congenital Hypothyroidism in Areas Covered by Kerman and Jiroft Universities of Medical Sciences, Iran. Health Dev J. 2012;1(1):47-55. [Article]
11. Amiri F, Sharifi H, Ghorbani E, Mirrashidi FS, Mirzaee M, Nasiri N. Prevalence of Congenital Hypothyroidism and Some Related Factors in Newborn Infants in Southern Kerman from April to March 2009. Iran J Epidemiol. 2019;15(2):188-94. [Article]
12. Doustmohamadian S, Mehrizi S, Rahbar MN, Mirmohammadkhani M. Congenital hypothyroidism and its related factors in an Iranian population: A retrospective study in Semnan (2011–2016). Int J Prev Med. 2020;11:169. [DOI] [PMID] [PMCID]
13. Dalili S, Rezvany SM, Dadashi A, Medghalchi A, Mohammadi H, Dalili H, et al. Congenital hypothyroidism: a review of the risk factors. Acta Med Iran. 2012;50(11):735-9. [PMID]
14. Deng K, He C, Zhu J, Liang J, Li X, Xie X, et al. Incidence of congenital hypothyroidism in China: data from the national newborn screening program, 2013–2015. J Pediatr Endocrinol Metab. 2018;31(6):601-8. [DOI] [PMID]
15. Minamitani K. Newborn screening for congenital hypothyroidism in Japan. Int J Neonatal Screen. 2021;7(3):34. [DOI] [PMID] [PMCID]
16. Maggio MC, Ragusa SS, Aronica TS, Granata OM, Gucciardino E, Corsello G. Neonatal screening for congenital hypothyroidism in an Italian Centre: a 5-years real-life retrospective study. Ital J Pediatr. 2021;47(1):108. [DOI] [PMID] [PMCID]
17. Abedi M, Shahsavari S, Salehi R, Hedayati Nia S, Nasrollahi S, Sadeghi S, et al. The study of prevalence and risk factors of hypothyroidism in newborn screening program in Sanandaj city in 2009-2014. Zanko J Med Sci. 2015;15(47):46-51. [Article]
18. Alimohamadi Y, Taghdir M, Sepandi M. Statistical data analysis of the risk factors of neonatal congenital hypothyroidism in Khuzestan province, Iran. Data Brief. 2018;21:2510-4. [DOI] [PMID] [PMCID]
19. Khammarnia M, Siakhulak FR, Ansari H, Peyvand M. Risk factors associated with congenital hypothyroidism: a case-control study in southeast Iran. Electron Physician. 2018;10(2):6286-91. [DOI] [PMID] [PMCID]
20. Esmailnasab N, Moasses Ghaffari B, Afkhamzadeh A. Investigation of the risk factors for congenital hypothyroidism in the newborns in Kurdistan Province. Sci J Kurdistan Univ Med Sci. 2012;17(4):103-8. [Article]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution 4.0 International License. |
