Journal of Occupational
Health and Epidemiology
Rafsanjan university Of medical sciences
Volume 14, Issue 4 (Autumn 2025)
J Occup Health Epidemiol 2025, 14(4): 256-267 |
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Momenabadi V, Doost-Mohammadi F, Saeedinezhad F, Ghazal N, Karampour A, Navabi M, et al . Epidemiology of Thyroid Cancer in Iran: Incidence, Disability-Adjusted Life Years (DALYs), and Association with Human Development Index (HDI) Using Global Burden of Disease (GBD) Data. J Occup Health Epidemiol 2025; 14 (4) :256-267
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Victoria Momenabadi1 
, Fatemeh Doost-Mohammadi2 , Fatemeh Saeedinezhad3 , Nima Ghazal4 , Ali Karampour5 , Mojgan Navabi6 , Behrooz Alipouryan Motlagh6 , Zaher Khazaei *7
, Fatemeh Doost-Mohammadi2 , Fatemeh Saeedinezhad3 , Nima Ghazal4 , Ali Karampour5 , Mojgan Navabi6 , Behrooz Alipouryan Motlagh6 , Zaher Khazaei *7
1- Assistant Prof. Dept of Public Health, School of Health, Bam University of Medical Sciences, Bam, Iran.
2- Ph.D. Student in Epidemiology, Clinical Research Development Unit, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.
3- M.Sc. in Epidemiology, Clinical Research Development Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
4- M.Sc. in Epidemiology, Student Research Committee, School of Public Health, Shahid Sadougi University of Medical Sciences of Yazd, Yazd, Iran.
5- M.Sc. in Health Services Management, School of Health Research Center for Health Sciences, Health Sciences & Technology Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.
6- B.Sc. in Public Health, Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
7- Ph.D. Student in Epidemiology, Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran. ,Zaherkhazaei@yahoo.com
2- Ph.D. Student in Epidemiology, Clinical Research Development Unit, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.
3- M.Sc. in Epidemiology, Clinical Research Development Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
4- M.Sc. in Epidemiology, Student Research Committee, School of Public Health, Shahid Sadougi University of Medical Sciences of Yazd, Yazd, Iran.
5- M.Sc. in Health Services Management, School of Health Research Center for Health Sciences, Health Sciences & Technology Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.
6- B.Sc. in Public Health, Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
7- Ph.D. Student in Epidemiology, Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran. ,
Article history
Received: 2025/05/27
Accepted: 2025/07/22
ePublished: 2025/12/13
Accepted: 2025/07/22
ePublished: 2025/12/13
Subject:
Epidemiology
Abstract: (29 Views)
Background: Thyroid cancer is the most common malignancy of the endocrine system. Given the differences in its frequency pattern across various parts of the world, understanding the frequency pattern of this cancer in Iran, as well as the burden of this disease, can play a key role in prevention and screening measures. This study aims to examine the incidence of disability-adjusted life years arising from thyroid cancer and the relationship between this disease and the Human Development Index (HDI).
Materials and Methods: This ecological study was undertaken by applying the Global Burden of Disease (GBD) study last version dataset (2021). It explored the pattern of incidence changes from 1990 to 2021 and calculated age—as well as sex-standardized incidence rates per 100,000 populations per year. Regression analysis was utilized to assess time trends and annual mean percentage changes. Finally, incidence rates were estimated separately for each province.
Results: The incidence of thyroid cancer in Iran has grown over the years. This disease's incidence varies across different regions of Iran and directly correlates with the HDI. In some areas, the annual average percentage change (AAPC) has exceeded 20%, indicating serious concern about the rise in this disease.
Conclusion: Overall, the burden of thyroid cancer in Iran has risen from 1990 to 2021, revealing a troubling trend. These changes can assist policymakers and researchers in understanding prevalence patterns as well as health needs more effectively, allowing them to design better programs for controlling and preventing this disease.
Materials and Methods: This ecological study was undertaken by applying the Global Burden of Disease (GBD) study last version dataset (2021). It explored the pattern of incidence changes from 1990 to 2021 and calculated age—as well as sex-standardized incidence rates per 100,000 populations per year. Regression analysis was utilized to assess time trends and annual mean percentage changes. Finally, incidence rates were estimated separately for each province.
Results: The incidence of thyroid cancer in Iran has grown over the years. This disease's incidence varies across different regions of Iran and directly correlates with the HDI. In some areas, the annual average percentage change (AAPC) has exceeded 20%, indicating serious concern about the rise in this disease.
Conclusion: Overall, the burden of thyroid cancer in Iran has risen from 1990 to 2021, revealing a troubling trend. These changes can assist policymakers and researchers in understanding prevalence patterns as well as health needs more effectively, allowing them to design better programs for controlling and preventing this disease.
Keywords: Thyroid Cancer [MeSH], Incidence [MeSH], Disability-Adjusted Life Years [MeSH], Iran [MeSH]
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