Volume 5, Number 1 (Winter 2016)                   JOHE 2016, 5(1): 45-52 | Back to browse issues page


XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Vazirinejad R, Jafarzadeh A, Yassini S, Rahimdel A, Sayadi A. Effectiveness of psychological training combined ‎with gradual muscular stress relaxation technique on quality of life of patients with multiple sclerosis . JOHE. 2016; 5 (1) :45-52
URL: http://johe.rums.ac.ir/article-1-172-en.html

PhD Student of Research Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Abstract:   (251 Views)

Background: Multiple sclerosis (MS) is one of the most common chronic diseases of the central nervous system. The aim of this study was to determine the effectiveness of psychological training combined‎ with gradual muscular stress relaxation technique on QOL of patients with MS.

Materials and Methods: This triple-blind, controlled, clinical trial was conducted on 60 patients with MS who were members of the Multiple Sclerosis Society of Yazd Province, Iran. The subjects were selected through convenience sampling method and with the consideration of the inclusion criteria. The participants were randomly divided into 2 groups of experimental (30 persons) and control (30 persons). The experimental group received 12 sessions of psychological training combined with gradual muscular stress relaxation technique (2 sessions per week), but the control group received no intervention. The data collection tools used consisted of a demographic characteristics form and the Multiple Sclerosis Quality of Life-54 (MSQOL-54) ‎ questionnaire. The questionnaires were completed before, immediately after, and 3 months after the training. Data were analyzed using the statistical tests of student’s t-test, Pearson correlation, and repeated measures.

Results: QOL score in the experimental and control groups were 50.86 ± 14.78 and 56.25 ± 13.09 before the intervention (p=0.141), 68.49 ± 11.81 and 55.76 ± 13.37 immediately after the intervention, and 67.80 ± 11.90 and 55.06 ± 12.83 three months after the intervention, respectively. This difference was statistically significant (P <0.0010). Moreover, repeated measures statistical test showed a meaningful increase in QOL score in the experimental group in the 3 measurements (P < 0.0001).

Conclusions: The implementation of psychological training intervention combined with gradual muscular stress relaxation method in patients with MS increases QOL. Therefore, it can be used as a beneficial intervention method for improving the QOL of patients with MS.

Full-Text [PDF 352 kb]   |   Full text (HTML)   (149 Downloads)    
Type of Study: original article | Subject: Occupational Health

1. Strober LB, Arnett PA. An examination of four models predicting fatigue in multiple sclerosis. Arch Clin Neuropsychol 2005; 20(5):631-46.
2. Joffe RT. Depression and multiple sclerosis: a potential way to understand the biology of major depressive illness. J Psychiatry Neurosci 2005; 30(1):9-10
3. McCabe MP. Mood and self-esteem of persons with multiple sclerosis following an exacerbation. J Psychosom Res 2005; 59(3):161-6.
4. Schulz KH, Gold SM, Witte J, Bartsch K, Lang UE, Hellweg R, et al. Impact of aerobic training on immune-endocrine parameters, neurotrophic factors, quality of life and coordinative function in multiple sclerosis. J Neurol Sci 2004; 225(1-2):11-8.
5. Ozakbas S, Cagiran I, Ormeci B, Idiman E. Correlations between multiple sclerosis functional composite, expanded disability status scale and health-related quality of life during and after treatment of relapses in patients with multiple sclerosis. J Neurol Sci 2004; 218(1-2):3-7.
6. Koopman W, Schweitzer A. The journey to multiple sclerosis: a qualitative study. J Neurosci Nurs 1999; 31(1):17-26.
7. Heydarpour P, Khoshkish S, Abtahi S, Moradi-Lakeh M, Sahraian MA. Multiple sclerosis epidemiology in Middle East and North Africa: A systematic review and meta-analysis. Neuroepidemiology 2015; 44(4):232-44.
8. The International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2 (WTCCC2), Sawcer S, Hellenthal G, Pirinen M, Spencer ChCA, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476(7359):214-9.
9. Ascherio A. Environmental factors in multiple sclerosis. Expert Rev Neurother 2013; 13(12 Suppl):3-9.
10. Etemadifar M, Sajjadi S, Nasr Z, Firoozeei TS, Abtahi SH, Akbari M, et al. Epidemiology of multiple sclerosis in Iran: a systematic review. Eur Neurol 2013; 70(5-6):356-63.
11. Abi Chahine NH, Rached JR, Abdelkarim AF, Hamade AA, Zoghbi VV. Treatment of long standing multiple sclerosis with regentime stem cell technique. Stem Cell Res Ther 2015; 5:8. doi: 10.4172/2157-7633.1000299.
12. Ropper AH, Brown RH. Adams and Victor's principles of neurology. 8th ed. 2 Pennsylvania Plaza New York, United States: McGraw-Hill Professional; 2005. P.961-75.
13. Koff MD, Cohen JA, McIntyre JJ, Carr CF, Sites BD. Severe brachial plexopathy after an ultrasound-guided single-injection nerve block for total shoulder arthroplasty in a patient with multiple sclerosis. Anesthesiology 2008; 108(2):325-8.
14. Gore-Felton C1, Koopman C, Spiegel D, Vosvick M, Brondino M, Winningham A. Effects of quality of life and coping on depression among adults living with HIV/AIDS. J Health Psychol 2006; 11(5):711-29.
15. Sousa KH, Kwok OM. Putting Wilson and Cleary to the test: analysis of a HRQOL conceptual model using structural equation modeling. Qual Life Res 2006; 15(4):725-37.
16. Patrick DL, Erickson P. Health status and health policy: Quality of life in health care evaluation and resource allocation. 1st ed. Oxford, England: Oxford University Press; 1993.
17. Lechner SC, Antoni MH, Lydston D, LaPerriere A, Ishii M, Devieux J, et al. Cognitive-behavioral interventions improve quality of life in women with AIDS. J Psychosom Res 2003; 54(3):253-61.
18. Beto JA, Bansal VK. Quality of life in treatment of hypertension. A meta-analysis of clinical trials. Am J Hypertens 1994; 5(3):125-33.
19. Deyo RA. The quality of life and research and care. Ann Intern Med 1991; 114(8):695-7.
20. Gu D, Reynolds K, Wu X, Chen J, Duan X, Muntner P, et al. Prevalence, awareness, treatment, and control of hypertension in China. Hypertension 2002; 40(6):920-7.
21. Watson M, Homewood J, Haviland, JS, Bliss JM. Influence of psychological response on breast cancer survival: 10-year follow-up of a population- based cohort. European Journal of Cancer 2005; 41(12):1710-4.
22. Marsh D. Working with families of people with serious mental illness. In: Vande Creek L, Knapp S, Jackson TL, editor. Innovations in clinical practice: A source book. Sarasota, FL: Professional Resource Press; 1992. P.389-402. (Vol. 11).
23. Capozzo MA, Martinis E, Pellis G, Giraldi T. An early structured psychoeducational intervention in patients with breast cancer: results from a feasibility study. Cancer Nurs 2010; 33(3):228-34.
24. Schreurs KM, de Ridder DT, Bensing JM. Fatigue in multiple sclerosis: reciprocal relationships with physical disabilities and depression. J Psychosom Res 2002; 53(3):775-81.
25. Ale-Yasin H, Sarai A, Alaeddini F, Ansarian E, Lotfi J. Multiple sclerosis: A study of 318 Iranian cases. Arch Iran Med 2002; 5(1):24-7.
26. Sá MJ. Psychological aspects of multiple sclerosis. Clinical neurology and neurosurgery 2008; 110(9):868-77.
27. Mitchell AJ, Benito-Leon J, Gonzalez JM, Rivera-Navarro J. Quality of life and its assessment in multiple sclerosis: integrating physical and psychological components of wellbeing. Lancet Neurol 2005; 4(9):556-66.
28. Fischer A, Heesen C, Gold SM. Biological outcome measurements for behavioral interventions in multiple sclerosis. Ther Adv Neurol Disord 2011; 4(4):217-29.
29. Ghaem H, Borhani Haghighi A, Jafari P, Nikseresht AR. Validity and reliability of the Persian version of the multiple sclerosis quality of life questionnaire. Neurol India 2007; 55(4):369-75.
30. Sangelaji B, Salimi Y, Dastoorpour M, Mansouri T, Ashrafinia F, Esmaeilzadeh N, et al. The relationship between disability and quality of life in multiple sclerosis patients. Journal of Health & Development 2013; 2(3):203-13.
31. Heidari Sureshjani S, Eslami AA, Hassanzadeh A. The quality of life among multiple sclerosis patients in Isfahan, Iran. Health System Research 2012; 7(5):571-9.
32. Somrarnyart M. Effectiveness of self-management training program among Thai cancer patients with pain. The Journal of Pain 2007; 8(4): S54.
33. Schulman-Green D, Bradley EH, Knobf MT, Prigerson H, DiGiovanna MP, McCorkle R. Self-management and transitions in women with advanced breast cancer. J Pain Symptom Manage 2011; 42(4): 517-25.
34. Masoodi R, Alhani F, Rabiei L, Majdinasab N, Moghaddasi J, Esmaeili SA, et al. The effect of family-centered empowerment model on quality of life and self efficacy of multiple sclerosis patients family care givers. Iranian Journal of Nursing Research 2013; 7(27):32-54.
35. Soleimani E, Habibi M, Basharpuor S. Effectiveness of self-control training on dimensions of quality of life in multiple sclerosis patients. Journal of Research in Behavioural Sciences 2013; 10(7):746-56.

Add your comments about this article : Your username or email:
Write the security code in the box

© 2015 All Rights Reserved | Journal of Occupational Health and Epidemiology

Designed & Developed by : Yektaweb