Volume 5, Number 2 (Spring 2016 2016)                   JOHE 2016, 5(2): 89-97 | Back to browse issues page


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Bateni E, Rabiei A, Ghanbarzadegan A. Comparison of periodontal parameters and metabolic glucose levels in patients with diabetes and healthy subjects. JOHE. 2016; 5 (2) :89-97
URL: http://johe.rums.ac.ir/article-1-204-en.html

Dentistry Student Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Dentistry Student, Clinical Research Development Center, Ali ebn Abitaleb Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Abstract:   (267 Views)

Background: For decades, it was suspected that diabetes contributed to poorer oral health and the increased frequency of periodontitis. More recently it was found that periodontitis could adversely affect glycemic control in diabetics. The aim of this study was to compare periodontal parameters with the metabolic sugar levels of diabetic and non-diabetic individuals.

Materials and Methods: In this cross-sectional study the experimental group were individuals with the diagnosis of diabetes. The control group consisted of healthy individuals without any systemic condition that affected periodontal status. Periodontal parameters, body mass index, HbA1c level and duration of diabetes were measured and recorded. Data were analyzed using Pearson’s correlation coefficient and Spearman’s correlation coefficient in a bivariate normal distribution.

Results: Patients with diabetes had worse periodontal status compared with control group. On the other hand, both patients with diabetes type 1 and 2 showed higher plaque index, bleeding index and clinical attachment loss compared with healthy control group. There was no meaningful relation between HbA1c and periodontal indices. In type 2 diabetic individuals, there was a significant correlation between the number of missing teeth and the duration of their illness.

Conclusions: Based on the evaluated parameters in this study, the experimental groups, (type 1 and 2 diabetics), experienced worse conditions than healthy control individuals with respect to their periodontal status. Deterioration of periodontal status is directly related to diabetes progression.

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Type of Study: original article | Subject: Special

1. AlJehani YA. Risk factors of periodontal disease: review of the literature. Int J Dent 2014; 2014:182513.
2. Bascones A, González J, Sanz J. Diabetes and periodontal disease. Review of the literature. Am J Dent 2014; 27(2):63-7.
3. Stanko P, Izakovicova Holla L. Bidirectional association between diabetes mellitus and inflammatory periodontal disease. A review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014; 158(1):35-8.
4. Geiss LS, Pan L, Cadwell B, Gregg EW, Benjamin SM, Engelgau MM. Changes in incidence of diabetes in US adults, 1997–2003. Am J Prev Med 2006; 30(5):371-7.
5. Campus G, Salem A, Uzzau S, Baldoni E, Tonolo G. Diabetes and periodontal disease: a case-control study. J Periodontol 2005; 76(3):418-25.
6. Lalla E, Park DB, Papapanou PN, Lamster IB. Oral disease burden in Northern Manhattan patients with diabetes mellitus. Am J Public Health 2004; 98(Suppl 1):S91-4.
7. Löe H. Periodontal disease: the sixth complication of diabetes mellitus. Diabetes Care 1993; 16(1):329-34.
8. Lösche W, Karapetow F, Pohl A, Pohl C, Kocher T. Plasma lipid and blood glucose levels in patients with destructive periodontal disease. J Clin Periodontol 2000; 27(8):537-41.
9. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest 2006; 116(7):1793-801.
10. Hayden P, Buckley LA. Diabetes mellitus and periodontal disease in an Irish population. J Periodontal Res 1989; 24(5):298-302.
11. Bullon P, Newman HN, Battino M. Obesity, diabetes mellitus, atherosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction? Periodontol 2000; 64(1):139-53.
12. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. N Engl J Med 2003; 348(17):1625-38.
13. Genco RJ, Grossi SG, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol 2005; 76(11 Suppl):2075-84.
14. Dalla Vecchia CF, Susin C, Rösing CK, Oppermann RV, Albandar JM. Overweight and obesity as risk indicators for periodontitis in adults. J Periodontol 2005; 76(10):1721-8.
15. Keller A, Rohde JF, Raymond K. Association between periodontal disease and overweight and obesity: a systematic review. J Periodontol 2015; 86(6):766-76.
16. Al-Zahrani MS, Bissada NF, Borawskit EA. Obesity and periodontal disease in young, middle-aged, and older adults. J Periodontol 2003; 74(5):610-5.
17. Nishida N, Tanaka M, Hayashi N, Nagata H, Takeshita T, Nakayama K, et al. Determination of smoking and obesity as periodontitis risks using the classification and regression tree method. J Periodontol 2005; 76(6):923-8.
18. Panwar SKh, Bhargava AK, Pandey I. Correlation between periodontal disease and diabetes mellitus. Indian Journal of Applied Research 2015; 5(10):202-3.
19. Pontes Andersen CC, Flyvbjerg A, Buschard K, Holmstrup P. Relationship between periodontitis and diabetes: lessons from rodent studies. J Periodontol 2007; 78(7):1264-75.
20. Carranza FA, Newman MG. Clinical periodontology. 8th ed. Philadelphia, United States: Walter Burns Saunders Co; 1996. P. 61-77.
21. Newman MG, Takei H, Klokkevold PR, Carranza FA. Carranza's clinical periodontology. 10th ed. Philadelphia, United States: Walter Burns Saunders Co Ltd; 2006. P.728-48
22. Armitage GC. Periodontal diseases: diagnosis. Ann Periodontol 1996; 1(1):37-215.
23. Vettore MV, Lamarca Gde A, Leão AT, Sheiham A, Leal Mdo C. Partial recording protocols for periodontal disease assessment in epidemiological surveys. Cad Saude Publica 2007; 23(1):33-42.
24. Sastrowijoto SH, van der Velden U, van Steenbergen TJ, Hillemans P, Hart AA, de Graaff J, et al. Improved metabolic control, clinical periodontal status and subgingival microbiology in insulin- dependent diabetes mellitus. J Clin Periodontol 1990; 17(4):233-42.
25. Cabała A, Chomyszyn-Gajewska M, Drozdz W. Periodontitis and systemic disease relationships. Przegl Lek 2006; 63(9):773-7.
26. Preshaw PM, Alba AL, Herrera D, Jepsen S, Konstantinidis A, Makrilakis K, et al. Periodontitis and diabetes: a two-way relationship. Diabetologia 2012; 55(1):21-31.
27. Taylor JJ, Preshaw PM, Lalla E. A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes. J Periodontol 2013; 84(4 Suppl):S113-34.
28. Tomita NE, Chinellato LE, Pernambuco RA, Lauris JR, Franco LJ; Grupo de Estudo Diabetes em Nipo-Brasileiros. Periodontal conditions and diabetes mellitus in the Japanese-Brazilian population. Rev Saude Publica 2002; 36(5):607-13.
29. Tervonen T, Oliver RC. Long-term control of diabetes mellitus and periodontitis. J Clin Periodontol 1993; 20(6):431-5.
30. Garcia D, Tarima S, Okunseri C. Periodontitis and glycemic control in diabetes: NHANES 2009 to 2012. J Periodontol 2015; 86(4):499-506.
31. Jansson H, Lindholm E, Lindh C, Groop L, Bratthall G. Type 2 diabetes and risk for periodontal disease: a role for dental health awareness. J Clin Periodontol 2006; 33(6):408-14.
32. Ilgüy M, Ilgüy D, Bayirli G. Dental lesions in adult diabetic patients. N Y State Dent J 2007; 73(1):58-6.
33. Hasegawa T, Watase H. Multiple risk factors of periodontal disease: a study of 9260 Japanese non-smokers. Geriatr Gerontol Int 2004; 4(1):37-43.

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