Volume 8, Issue 3 (Summer 2019)                   J Occup Health Epidemiol 2019, 8(3): 118-122 | Back to browse issues page


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Meskini M, Farhadi S, Esmaeili D. Antibiotic resistance in patients referred to Ali-ebn Abi-Taleb Hospital, Qom, Iran (2014-2015). J Occup Health Epidemiol 2019; 8 (3) :118-122
URL: http://johe.rums.ac.ir/article-1-353-en.html

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1- PhD Student, Department of Microbiology and Microbiology Research Center, Pasteur Institute, Tehran, Iran; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran.
2- BSc Student, Department of Microbiology and Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
3- Associate Prof., Department of Microbiology and Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran; Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. , esm114@gmail.com
Article history
Received: 2019/07/13
Accepted: 2019/10/13
ePublished: 2020/01/23
Subject: Epidemiology
Abstract:   (3295 Views)
Background: In recent years, the risk of acquiring antibiotic resistance has been increasing due to the widespread use of antibiotics. This study aims to evaluate the antibiotic resistance pattern in patients referred to Ali-ebn Abi-Taleb hospital.
Materials and Methods: In a descriptive study, samples of urine, blood, cerebrospinal fluid, and body fluid were collected from patients referred to Ali-ebn Abi-Taleb Hospital from September 2014 to February 2015. Of these, 687 isolates identified as E. coli were tested for antibiotic susceptibility against 15 antibiotics by the Kirby- Bauer method based on CLSI 2015. The relevant prevalence, percentage, and mean were reported using SPSS (version 16).
Results: A total of 10824 samples were collected. A total of 866 isolates were grown on an agar medium, and 80.3% of the samples were isolated from women. The highest rate of antibiotic resistance was reported to be for Amoxicillin (82.2%). The lowestrate of antibiotic resistance was reported against Nitrofurantoin (14%).
Conclusions: We concluded there is an increasing rate of antibiotic resistance among E. coli isolates. Therefore, the necessity of identifying drug resistance is apparent using precise and straightforward methods to prevent the extensive distribution of antibiotic resistantagents.

 
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References
1. Issakhanian L, Behzadi P. Antimicrobial Agents and Urinary Tract Infections. Curr Pharm Des 2019; 25(12):1409-23. [DOI] [PMID]
2. Basak S, Singh P, Rajurkar M. Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study. J Pathog 2016; 2016:4065603. [DOI] [PMID] [PMCID]
3. Ramos NL, Saayman ML, Chapman TA, Tucker JR, Smith HV, Faoagali J, et al. Genetic relatedness and virulence gene profiles of Escherichia coli strains isolated from septicaemic and uroseptic patients. Eur J Clin Microbiol Infect Dis 2010; 29(1):15-23. [DOI] [PMID]
4. Shrestha LB, Baral R, Poudel P, Khanal B. Clinical, etiological and antimicrobial susceptibility profile of pediatric urinary tract infections in a tertiary care hospital of Nepal. BMC Pediatr 2019; 19(1):36. [DOI] [PMID] [PMCID]
5. Uppala A, King EA, Patel D. Cefazolin versus fluoroquinolones for the treatment of community-acquired urinary tract infections in hospitalized patients. Eur J Clin Microbiol Infect Dis 2019; 38(8):1533-8. [DOI] [PMID]
6. Falciglia G, Hageman JR, Schreiber M, Alexander K. Antibiotic Therapy and Early Onset Sepsis. Neoreviews 2012; 13(2):e86-93. [DOI]
7. Abdel-Raouf M, Aldeweik HM, Albannan MS, Zaki MM, Abdelkader AE, Moemen D. Influence of Different Families of Commercial Antibiotics on Controlling Nosocomial Infections. South Asian Journal of Research in Microbiology 2019; 4(2):1-8. [Article] [DOI]
8. Midturi JK, Ranganath S. Prevention and Treatment of Multidrug-Resistant Organisms in End-Stage Renal Disease. Adv Chronic Kidney Dis 2019; 26(1):51-60. [DOI] [PMID]
9. Niranjan V, Malini A. Antimicrobial resistance pattern in Escherichia coli causing urinary tract infection among inpatients. Indian J Med Res 2014; 139(6):945-8. [PMID] [PMCID]
10. Kakian F, Shahini Shams Abadi M, Gholipour A, Fadaie M, Zamanzad B, Khairi S, et al. Evaluating the prevalence of virulence genes of Escherichia coli in patients affected by urinary tract infection. Gene Rep 2019; 16:100433. [Article] [DOI]
11. Paulshus E, Thorell K, Guzman-Otazo J, Joffre E, Colque P, Kühn I, et al. Repeated Isolation of Extended-Spectrum-β-Lactamase-Positive Escherichia coli Sequence Types 648 and 131 from Community Wastewater Indicates that Sewage Systems are Important Sources of Emerging Clones of Antibiotic-Resistant Bacteria. Antimicrob Agents Chemother 2019; 63(9). [DOI] [PMID] [PMCID]
12. Sib E, Voigt AM, Wilbring G, Schreiber C, Faerber HA, Skutlarek D, et al. Antibiotic resistant bacteria and resistance genes in biofilms in clinical wastewater networks. Int J Hyg Environ Health 2019; 222(4):655-62. [DOI] [PMID]
13. Tille P. Bailey & Scott's Diagnostic Microbiology - E - Book. 14th ed. Maryland Heights, Missouri, United States: Mosby; 2015.
14. Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: A review. J Pharm Anal 2016; 6(2):71-9. [DOI] [PMID] [PMCID]
15. Pourmand MR, Keshtvarz M, Soltan Dallal MM, Talebi M, Bakhtiari R, Pourmand Gh. Urinary tract infection in renal transplant patients in Sina University Hospital. Tehran University Medical Journal 2013; 71(2):114-21. [Article]
16. Asadi Manesh F, Sharifi A, Mohammad Hosini Z, Nasrolahi H, Hosseini N, Kalantari A, et al. Antibiotic Resistance of Urinary Tract Infection of Children Under 14 Years Admitted To The Pediatric Clinic of Imam Sajjad Hospital, 2012. Armaghan-e-Danesh 2014; 19(5):411-20. [Article]
17. Chuang P, Parikh CR, Langone A. Urinary tract infections after renal transplantation: a retrospective review at two US transplant centers. Cli Transplant 2005; 19(2):230-5. [DOI] [PMID]
18. Pourmand G, Salem S, Mehrsai A, Taherimahmoudi M, Ebrahimi R, Pourmand MR. Infectious complications after kidney transplantation: a single‐center experience. Transpl Infect Dis 2007; 9(4):302-9. [DOI] [PMID]
19. Manouchehri M, Ahanjan M. Detection of CTX beta-lactamase Gene in Escherichia Coli Isolated from Urinary Tract Infection Using Polymeras Chain Reaction. Journal of Mazandaran University of Medical Sciences 2015; 25(129):36-45. [Article]
20. Oteo J, Navarro C, Cercenado E, Delgado-Iribarren A, Wilhelmi I, Orden B, et al. Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions. J Clin Microbiol 2006; 44(7):2359-66 [DOI] [PMID] [PMCID]
21. Khan AU, Zaman MS. Multiple drug resistance pattern in Urinary Tract Infection patients in Aligarh. Biomed Res (Aligarh) 2006; 17(3):179-81. [Article]
22. Karlowsky JA, Kelly LJ, Thornsberry C, Jones ME, Sahm DF. Trends in antimicrobial resistance among urinary tract infection isolates of Escherichia coli from female outpatients in the United States. Antimicrob Agents Chemother 2002; 46(8):2540-5. [DOI] [PMID] [PMCID]

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